Juvenile familial mosaic degeneration of the cornea associated with megalocornea.

TBE classification of the heredo-familial degenerations of the cornea proposed by Franceschetti and Fomi (1950) and Franceschetti (1954), includes among the degenerations of the anterior limiting membrane (Bowman's) a rather rare manifestation called "mosaic degeneration". Because of its rarity, and because of certain unusual features, we have considered it worth while to report three cases recently observed. The patients were three out of five brothers (Fig. 1), the oldest and the youngest ofwhom showed no ocular abnormalities. The father and mother had both been dead for some time but, according to their sons, they had enjoyed good eyesight until late in life. As far as could be ascertained there was no consangulinity.